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Multiple Choice

In rheumatoid arthritis, which cervical spine complication can occur?

Rheumatoid arthritis commonly affects the cervical spine in a way that can threaten the spinal cord, with atlantoaxial subluxation being a hallmark complication. Chronic inflammatory synovitis and degradation of ligaments around the C1–C2 junction, especially the transverse ligament that holds the dens against the atlas, lead to instability between these two vertebrae. When this ligament becomes lax or disrupted, the atlas can slip forward on the axis, widening the atlantodental interval and risking spinal cord compression. This instability can produce neck pain and, more seriously, myelopathy or even rapid neurological deterioration after minor trauma. The key to recognition is dynamic imaging: flexion-extension cervical spine X-rays can show an increased atlantodental distance, and MRI helps assess any cord compression. Management starts with immobilization and close monitoring; surgical stabilization, typically a posterior fusion, is considered if there is neurologic impairment or progressive subluxation despite conservative measures. Other cervical spine issues listed, such as anterior spondylolisthesis, osteophyte formation, or disc herniation, are not characteristically driven by rheumatoid inflammatory processes in the same way atlantoaxial subluxation is.

Rheumatoid arthritis commonly affects the cervical spine in a way that can threaten the spinal cord, with atlantoaxial subluxation being a hallmark complication. Chronic inflammatory synovitis and degradation of ligaments around the C1–C2 junction, especially the transverse ligament that holds the dens against the atlas, lead to instability between these two vertebrae. When this ligament becomes lax or disrupted, the atlas can slip forward on the axis, widening the atlantodental interval and risking spinal cord compression.

This instability can produce neck pain and, more seriously, myelopathy or even rapid neurological deterioration after minor trauma. The key to recognition is dynamic imaging: flexion-extension cervical spine X-rays can show an increased atlantodental distance, and MRI helps assess any cord compression. Management starts with immobilization and close monitoring; surgical stabilization, typically a posterior fusion, is considered if there is neurologic impairment or progressive subluxation despite conservative measures.

Other cervical spine issues listed, such as anterior spondylolisthesis, osteophyte formation, or disc herniation, are not characteristically driven by rheumatoid inflammatory processes in the same way atlantoaxial subluxation is.