Gout is a syndrome caused by deposition of which type of crystals in tissues?

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Multiple Choice

Gout is a syndrome caused by deposition of which type of crystals in tissues?

Explanation:
Gout results from deposition of monosodium urate crystals in tissues when uric acid levels are elevated. These needle-shaped crystals are negatively birefringent under polarized light and tend to settle in cooler joints, provoking a powerful inflammatory reaction that causes the sudden, painful swelling of an acute gout attack. Chronic crystal deposition can form tophi in soft tissues. Calcium pyrophosphate crystals cause pseudogout and are rhomboid-shaped with weak positive birefringence, not the needle-like, negatively birefringent crystals seen in gout. Cholesterol crystals and hydroxyapatite crystals are involved in other conditions and do not describe gout crystal deposition.

Gout results from deposition of monosodium urate crystals in tissues when uric acid levels are elevated. These needle-shaped crystals are negatively birefringent under polarized light and tend to settle in cooler joints, provoking a powerful inflammatory reaction that causes the sudden, painful swelling of an acute gout attack. Chronic crystal deposition can form tophi in soft tissues.

Calcium pyrophosphate crystals cause pseudogout and are rhomboid-shaped with weak positive birefringence, not the needle-like, negatively birefringent crystals seen in gout. Cholesterol crystals and hydroxyapatite crystals are involved in other conditions and do not describe gout crystal deposition.

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