“Basic therapy" in osteoporosis

• A. Calcium plus Vitamin D3
• B. Biological therapy
• C. Analgetics
• D. NSAID

Answer: (A)

The main idea here is that managing osteoporosis starts with correcting mineral and hormonal factors that drive bone strength. Providing enough calcium and vitamin D addresses the core need for proper bone mineralization. Calcium supplies the building blocks for bone, while vitamin D increases calcium absorption from the gut and helps regulate parathyroid hormone, which, if elevated, promotes bone breakdown. Together, they create a favorable environment for bone remodeling and help reduce fracture risk, making them the foundational therapy in most patients.

Biological therapies, such as antiresorptives or anabolic agents, are important for many with osteoporosis but are considered when higher risk or inadequate response exists beyond basic measures. Analgesics and NSAIDs treat pain and inflammation but do not modify bone metabolism or prevent fractures, so they don’t constitute the basic disease-modifying therapy. In practice, a typical approach aims for adequate calcium intake and vitamin D supplementation, with additional osteoporosis-directed treatments as needed based on risk assessment.